Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14549
Abstract: Senile plaques are a pathological hallmark of Alzheimer's disease (AD), yet the mechanism underlying their generation remains unknown. Beta‐amyloid peptide (Aβ) is a major component of senile plaques. We analysed AD brain tissues with histochemistry,… read more here.
Keywords: senile plaques; alzheimer disease; microaneurysm; intravascular haemolysis ... See more keywords
Neonatal exposure to aluminum chloride predisposes adult and senile gerbils to the prostatic hyperplasia
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DOI: 10.1002/cbin.11995
Abstract: Several pollutants can alter neonatal prostatic development predisposing this gland to diseases. The toxicity and endocrine disrupting potential of aluminum has been reported in many organs, but little is known about its effects on the… read more here.
Keywords: aluminum chloride; neonatal exposure; prostate; prostatic hyperplasia ... See more keywords
Senile Lemierre syndrome complicated with descending necrotizing mediastinitis
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DOI: 10.1097/md.0000000000011903
Abstract: Rationale: Senile patients with LS complicated with DNM are rarely seen in clinical practice, and extensive cervical incision and drainage plus administration of effective antibiotics are the basis for treatment. Currently, the treatment controversy mainly… read more here.
Keywords: incision drainage; cervical incision; treatment; senile ... See more keywords
Network analysis combined with experimental assessment to explore the therapeutic mechanisms of New Shenqi Pills formula targeting mitochondria on senile diabetes mellitus
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2024.1339758
Abstract: Background The escalation of global population aging has accentuated the prominence of senile diabetes mellitus (SDM) as a consequential public health concern. Oxidative stress and chronic inflammatory cascades prevalent in individuals with senile diabetes significantly… read more here.
Keywords: senile; diabetes mellitus; analysis; senile diabetes ... See more keywords