Articles with "senile plaque" as a keyword



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The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives

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Published in 2023 at "Brain and Behavior"

DOI: 10.1002/brb3.2953

Abstract: The morphology of senile plaques depends on the APP knock‐in mice brain fixative. Solid forms of senile plaques were detected in APP knock‐in mice after formic acid treatment with Davidson's and Bouin's fluid fixative as… read more here.

Keywords: knock mice; senile plaque; plaque morphological; morphological differences ... See more keywords
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Alzheimer’s senile plaque as shown by microcryodissection, a new technique for dissociating tissue structures

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Published in 2017 at "Journal of Neural Transmission"

DOI: 10.1007/s00702-017-1718-7

Abstract: Extracellular accumulation of Aβ peptides and intracellular aggregation of hyperphosphorylated tau proteins are the two hallmark lesions of Alzheimer disease (AD). The senile plaque is made of a core of extracellular Aβ surrounded by phospho-tau… read more here.

Keywords: technique; tissue; senile plaque; plaque ... See more keywords