Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14549
Abstract: Senile plaques are a pathological hallmark of Alzheimer's disease (AD), yet the mechanism underlying their generation remains unknown. Beta‐amyloid peptide (Aβ) is a major component of senile plaques. We analysed AD brain tissues with histochemistry,… read more here.
Keywords: senile plaques; alzheimer disease; microaneurysm; intravascular haemolysis ... See more keywords
A History of Senile Plaques: From Alzheimer to Amyloid Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlac030
Abstract: Senile plaques have been studied in postmortem brains for more than 120 years and the resultant knowledge has not only helped us understand the etiology and pathogenesis of Alzheimer disease (AD), but has also pointed to… read more here.
Keywords: senile plaques; plaques alzheimer; alzheimer amyloid; amyloid imaging ... See more keywords