Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer cell"
DOI: 10.1016/j.ccell.2018.01.020
Abstract: Trait-associated loci often map to genomic regions encoding long noncoding RNAs (lncRNAs), but the role of these lncRNAs in disease etiology is largely unexplored. We show that a pair of sense/antisense lncRNA (6p22lncRNAs) encoded by… read more here.
Keywords: pair; sense antisense; antisense lncrna; sox9 ... See more keywords
Sense and antisense RNA products of the uxuR gene can affect motility and chemotaxis acting independent of the UxuR protein
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1121376
Abstract: Small non-coding and antisense RNAs are widespread in all kingdoms of life, however, the diversity of their functions in bacteria is largely unknown. Here, we study RNAs synthesised from divergent promoters located in the 3′-end… read more here.
Keywords: sense antisense; motility chemotaxis; gene; uxur gene ... See more keywords
Making Sense of Antisense lncRNAs in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108886
Abstract: Transcriptome complexity is emerging as an unprecedented and fascinating domain, especially by high-throughput sequencing technologies that have unveiled a plethora of new non-coding RNA biotypes. This review covers antisense long non-coding RNAs, i.e., lncRNAs transcribed… read more here.
Keywords: antisense lncrnas; sense antisense; hepatocellular carcinoma; sense ... See more keywords
Epigenetic Regulation of HIV-1 Sense and Antisense Transcription in Response to Latency-Reversing Agents
Sign Up to like & getrecommendations! Published in 2023 at "Non-Coding RNA"
DOI: 10.3390/ncrna9010005
Abstract: Nucleosomes positioned on the HIV-1 5′ long terminal repeat (LTR) regulate sense transcription as well as the establishment and maintenance of latency. A negative-sense promoter (NSP) in the 3′ LTR expresses antisense transcripts with coding… read more here.
Keywords: transcription; latency reversing; sense antisense; reversing agents ... See more keywords
Making Sense of Antisense Oligonucleotide Therapeutics Targeting Bcl-2
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14010097
Abstract: The B-cell lymphoma 2 (Bcl-2) family, comprised of pro- and anti-apoptotic proteins, regulates the delicate balance between programmed cell death and cell survival. The Bcl-2 family is essential in the maintenance of tissue homeostasis, but… read more here.
Keywords: antisense oligonucleotide; sense antisense; making sense; oligonucleotide therapeutics ... See more keywords