Exploring 5'-Biotinylation of the Sense Strand to Improve siRNA Specificity and Potency.
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DOI: 10.1007/978-1-0716-0290-4_9
Abstract: Although RNA interference is widely used for gene silencing, unintended gene modulation generated by off-target effects represents a major barrier to its applications in biology and medicine. Off-targeting can be induced by both the sense and antisense… read more here.
Keywords: sense strand; potency; sense; strand ... See more keywords