Endomembrane damage sensing by V-ATPase recruits ATG16L1 for LC3 lipidation in situ.
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DOI: 10.1080/15548627.2022.2062889
Abstract: LC3 lipidation-mediated selective macroautophagy/autophagy helps eukaryotes to defend against endogenous dangers and foreign invaders. However, LC3 activation mechanisms of selective autophagy are still elusive. We previously determined that the V-ATPase-ATG16L1 axis is critical for LC3… read more here.
Keywords: lipidation; lc3 lipidation; sensing atpase; damage sensing ... See more keywords