Expanding, integrating, sensing and responding: the role of primary metabolism in specialised metabolite production.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2019.03.006
Abstract: Producing specialised metabolites such as antibiotics, immunosuppressives, anti-cancer agents and anti-helminthics draws on primary metabolism to provide the building blocks for biosynthesis. The growth phase-dependent nature of production means that producing organisms must deal with… read more here.
Keywords: specialised metabolite; metabolism; metabolite production; primary metabolism ... See more keywords
Sensing and Responding of Cardiomyocytes to Changes of Tissue Stiffness in the Diseased Heart
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.642840
Abstract: Cardiomyocytes are permanently exposed to mechanical stimulation due to cardiac contractility. Passive myocardial stiffness is a crucial factor, which defines the physiological ventricular compliance and volume of diastolic filling with blood. Heart diseases often present… read more here.
Keywords: myocardial stiffness; heart; stiffness; biology ... See more keywords