Paired Derivatization Approach with H/D-Labeled Hydroxylamine Reagents for Sensitive and Accurate Analysis of Monosaccharides by Liquid Chromatography Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04924
Abstract: Monosaccharides play important roles in biological processes. Sensitive and accurate analyses of monosaccharides remain challenging because of their high hydrophilicities and poor ionization efficiencies. Here, we developed a paired derivatization approach with H/D-labeled hydroxylamines for… read more here.
Keywords: monosaccharides liquid; paired derivatization; derivatization approach; sensitive accurate ... See more keywords
Metastable Dumbbell Probe-Based Hybridization Chain Reaction for Sensitive and Accurate Imaging of Intracellular-Specific MicroRNAs In Situ in Living Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b05920
Abstract: Sensitive and accurate imaging of intracellular-specific microRNAs (miRNAs) in situ in living cells is seriously challenged by the susceptibility of nucleic acid probes and the low dynamics of the hybridization reaction in cellular environments. Herein,… read more here.
Keywords: accurate imaging; intracellular specific; sensitive accurate; hybridization ... See more keywords
Sensitive and accurate analysis of gene expression signatures enabled by oligonucleotide-labelled cDNA
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2078093
Abstract: ABSTRACT High-throughput RNA sequencing offers a comprehensive analysis of transcriptome complexity originated from regulatory events, such as differential gene expression, alternative polyadenylation and others, and allows the increase in diagnostic capacity and precision. For gene… read more here.
Keywords: analysis; sensitive accurate; gene expression; gene ... See more keywords
TreeSAPP: the Tree-based Sensitive and Accurate Phylogenetic Profiler
Sign Up to like & getrecommendations! Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa588
Abstract: Abstract Motivation Microbial communities drive matter and energy transformations integral to global biogeochemical cycles, yet many taxonomic groups facilitating these processes remain poorly represented in biological sequence databases. Due to this missing information, taxonomic assignment… read more here.
Keywords: phylogenetic profiler; accurate phylogenetic; sensitive accurate; based sensitive ... See more keywords
Abstract 2756: Multiplexing done differently: flexible, sensitive, and accurate detection of miRNA and protein analytes using Firefly particle technology
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-2756
Abstract: Detection of molecular biomarkers in biological fluids is used as an indicator of normal biological processes, pathogenic processes, and response to therapeutic intervention1,2. Using a combined signature of multiple biomarkers can better account for patient… read more here.
Keywords: detection; protein analytes; sensitive accurate; using firefly ... See more keywords
A sensitive and accurate test for simultaneous detection of 36 BRAF and NRAS mutations.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e24153
Abstract: e24153Background: Activating mutations in the mitogen-activated protein kinase pathway are among the most common mutations found in cancer cells. Because of the interaction between BRAF and NRAS, t... read more here.
Keywords: sensitive accurate; accurate test; simultaneous detection; test simultaneous ... See more keywords