When used together SS18–SSX fusion‐specific and SSX C‐terminus immunohistochemistry are highly specific and sensitive for the diagnosis of synovial sarcoma and can replace FISH or molecular testing in most cases
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DOI: 10.1111/his.14190
Abstract: Synovial sarcoma is defined by recurrent t(X;18)(p11;q11) translocations creating SS18–SSX1, SS18–SSX2 or SS18–SSX4 fusions. Recently, a novel rabbit monoclonal antibody designed to identify these fusions (SS18–SSX, clone E9X9V) was proposed to be highly specific (100%),… read more here.
Keywords: sensitive diagnosis; synovial sarcoma; highly specific; ss18 ssx ... See more keywords