Articles with "sensitive genes" as a keyword



Network-based transcriptomic analysis reveals novel melatonin-sensitive genes in cardiovascular system

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Published in 2019 at "Endocrine"

DOI: 10.1007/s12020-019-01925-w

Abstract: PurposeHeart disease is a major cause of mortality and disability worldwide. Melatonin is a neuroendocrine hormone and has been found to be protective in heart disease. However, the molecular basis underlying this cardioprotective effect is… read more here.

Keywords: sensitive genes; analysis; genes cardiovascular; melatonin sensitive ... See more keywords

Evolution of Dosage-Sensitive Genes by Tissue-Restricted Expression Changes

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Published in 2024 at "Genome Biology and Evolution"

DOI: 10.1101/2024.10.17.618887

Abstract: Dosage-sensitive genes have characteristic patterns of evolution that include being refractory to small-scale duplication, depleted on human benign copy number variants (CNVs) and enriched on pathogenic CNVs. This intolerance to copy number change is likely… read more here.

Keywords: evolution; dosage sensitive; dosage; sensitive genes ... See more keywords

Atopic Patients Show Increased Interleukin 4 Plasma Levels but the Degree of Elevation Is Not Sufficient to Upregulate Interleukin-4-Sensitive Genes

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Published in 2019 at "Skin Pharmacology and Physiology"

DOI: 10.1159/000499431

Abstract: Background: Atopic diseases constitute a major health challenge for industrialized countries, and elevated levels of interleukin 4 (IL-4) frequently characterize these disorders. Previous in vitroanalyses have indicated that IL-4 strongly upregulates the expression of IL-4-sensitive… read more here.

Keywords: atopic patients; sensitive genes; expression; degree elevation ... See more keywords

The sensitive genes in response to various metal ion stresses in the yeast Saccharomyces cerevisiae.

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Published in 2022 at "Protein and peptide letters"

DOI: 10.2174/0929866529666220126102348

Abstract: Yeast Saccharomyces cerevisiae is a good eukaryotic model for studying the molecular mechanism of toxic metal ion stress. Numerous studies have been performed on the signal transduction induced by toxic metal ion stress. The physiological… read more here.

Keywords: metal ion; sensitive genes; ion stress; ion ... See more keywords