Defective minor spliceosomes induce SMA-associated phenotypes through sensitive intron-containing neural genes in Drosophila
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DOI: 10.1038/s41467-020-19451-z
Abstract: The minor spliceosome is evolutionarily conserved in higher eukaryotes, but its biological significance remains poorly understood. Here, by precise CRISPR/Cas9-mediated disruption of the U12 and U6atac snRNAs, we report that a defective minor spliceosome is… read more here.
Keywords: associated phenotypes; intron containing; sma associated; sensitive intron ... See more keywords