Efficient Mucosal Immunization by Mucoadhesive and pH-Sensitive Polymeric Vaccine Delivery System
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular Research"
DOI: 10.1007/s13233-019-7042-3
Abstract: Mucosal surfaces as the largest immune organ of human body cover 400 m2 of the body including the gastrointestinal, urogenital, and respiratory tracts. The local mucosal immunity is an important first line of defense against… read more here.
Keywords: sensitive polymeric; vaccine delivery; mucosal; mucoadhesive sensitive ... See more keywords
Reactive oxygen species-sensitive polymeric nanocarriers for synergistic cancer therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.05.023
Abstract: Reactive oxygen species (ROS)-responsive nanocarriers have aroused widespread interest in recent years. On the one hand, a high ROS level has been detected in many types of tumor cells. On the other hand, ROS generation… read more here.
Keywords: reactive oxygen; sensitive polymeric; oxygen species; polymeric nanocarriers ... See more keywords
pH-Sensitive Polymeric Vesicles for GOx/BSO Delivery and Synergetic Starvation-Ferroptosis Therapy of Tumor.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00960
Abstract: Typical glucose oxidase (GOx)-based starvation therapy is a promising strategy for tumor treatment; however, it is still difficult to achieve an effective therapeutic effect via a single starvation therapy. Herein, we designed a pH-sensitive polymeric… read more here.
Keywords: sensitive polymeric; starvation; ferroptosis; gox bso ... See more keywords
Abstract LB336: pH-sensitive polymeric micelles loading IL-12 profoundly inflame the tumor microenvironment to eradicate cold tumors
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb336
Abstract: Background: Treatment of immunologically cold tumors is a major challenge. IL-12 can activates both innate and adaptive immunity to elicit strong antitumor immunity. Nevertheless, the poor pharmacokinetic and severe side effects of IL-12 limit the… read more here.
Keywords: micelles loading; cold tumors; eradicate cold; sensitive polymeric ... See more keywords
Redox-Sensitive Polymeric Micelles Based on Tetraphenylethylene-Conjugated Copolymer for Aggregation-Induced Emission Active Imaging and Drug Delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2017.2440
Abstract: Intelligent nanocarriers for efficient drug delivery and bioimaging application are urgently demand. Herein, paclitaxel (PTX)-encapsulated redox-sensitive polymeric micelles based on tetraphenylethylene (TPE)-conjugated poly(D, L-lactide)-disulfide-poly(methacryloyloxyethyl phosphorylcholine) (TPE-PLA-SS-PMPC) copolymer has been developed for combined cancer therapy and… read more here.
Keywords: sensitive polymeric; drug delivery; redox sensitive; drug ... See more keywords