High Purity Isolation and Sensitive Quantification of Extracellular Vesicles Using Affinity to TIM4
Sign Up to like & getrecommendations! Published in 2017 at "Current Protocols in Cell Biology"
DOI: 10.1002/cpcb.32
Abstract: Almost all types of cells secrete extracellular vesicles (EVs), including exosomes and microvesicles. EVs carry various proteins, lipids, mRNAs, and microRNAs, and may participate in many aspects of physiological and pathophysiological processes. Various studies are… read more here.
Keywords: extracellular vesicles; affinity; sensitive quantification; evs ... See more keywords
A multiplex sensitive quantification of microRNAs based on competitive PCR
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-016-0364-5
Abstract: MicroRNAs (miRNAs) are endogenous ~22 nt RNAs that play important regulatory roles in animals and plants by targeting mRNAs for cleavage or gene silencing. Although quantitative real-time PCR (qRT-PCR) had been widely used for miRNAs… read more here.
Keywords: mir 505; sensitive quantification; pcr; cpcr ... See more keywords
Highly sensitive quantification for human plasma-targeted metabolomics using an amine derivatization reagent.
Sign Up to like & getrecommendations! Published in 2017 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2016.11.068
Abstract: Amino acids and their related metabolites play important roles in various physiological processes and have consequently become biomarkers for diseases. However, accurate quantification methods have only been established for major compounds, such as amino acids… read more here.
Keywords: quantification; highly sensitive; derivatization reagent; sensitive quantification ... See more keywords
A General Signal Amplifier of Self-Assembled DNA Micelles for Sensitive Quantification of Biomarkers.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05415
Abstract: Owing to the excellent structural rigidity and programmable reaction sites, DNA nanostructures are more and more widely used, but they are limited by high cost, strict sequence requirements, and time-consuming preparation. Herein, a general signal… read more here.
Keywords: general signal; signal amplifier; dna; quantification biomarkers ... See more keywords
Sensitive quantification of m.3243A>G mutational proportion in non-retinal tissues and its relationship with visual symptoms.
Sign Up to like & getrecommendations! Published in 2021 at "Human molecular genetics"
DOI: 10.1093/hmg/ddab289
Abstract: The m.3243A>G mutation in the mitochondrial genome commonly causes retinal degeneration in patients with maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). Like other mitochondrial mutations, m.3243A>G is… read more here.
Keywords: sensitive quantification; quantification 3243a; visual symptoms; 3243a mutational ... See more keywords
Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI–IM–MS/MS Assay
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12071897
Abstract: The third-generation tyrosine kinase inhibitor (TKI), osimertinib, has revolutionized the treatment of patients with non-small cell lung carcinoma with epidermal growth factor receptor (EGFR)-activating mutation, and resistant to first- and second-generation TKIs. Osimertinib is now… read more here.
Keywords: medicine; plasma; sensitive quantification; quantification osimertinib ... See more keywords