First highly sensitive and specific competitive ELISA for detection of bovine besnoitiosis with potential as a multi-species test.
Sign Up to like & getrecommendations! Published in 2020 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2019.12.010
Abstract: Serological cross-reactions represent a serious problem in some currently available tests to diagnose Besnoitia infections in many species including cattle, caribou and donkeys. False-positive results are due to the low positive-predictive value (PPV) of these… read more here.
Keywords: specific competitive; besnoitiosis; highly sensitive; sensitive specific ... See more keywords
A highly sensitive and specific lateral flow aptasensor for the detection of human osteopontin.
Sign Up to like & getrecommendations! Published in 2020 at "Talanta"
DOI: 10.1016/j.talanta.2019.120624
Abstract: The rapid determination of human osteopontin (OPN) protein, a potential cancer biomarker, holds substantial promise for point-of-care diagnostics and biomedical applications. To date, most reported platforms for OPN detection are apparatus-dependent, time-consuming, and expensive. Herein,… read more here.
Keywords: detection; highly sensitive; human osteopontin; sensitive specific ... See more keywords
Sensitive and Specific Colorimetric Detection of Cancer Cells Based on Folate-Conjugated Gold–Iron-Oxide Composite Nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "ACS Applied Nano Materials"
DOI: 10.1021/acsanm.9b01947
Abstract: A sensitive and specific colorimetric analytical strategy for cancer-cell detection based on folate-conjugated gold–iron-oxide composite nanoparticles (Au-Fe2O3 CNPs) has been developed. The synthe... read more here.
Keywords: specific colorimetric; based folate; gold iron; folate conjugated ... See more keywords
Highly sensitive and specific Alu-based quantification of human cells among rodent cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13402-3
Abstract: Alu elements are primate-specific short interspersed elements (SINEs), over 1 million copies of which are present in the human genome; thus, Alu elements are useful targets for detecting human cells. However, previous Alu-based techniques for… read more here.
Keywords: alu based; highly sensitive; sensitive specific; rodent cells ... See more keywords
Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra06758b
Abstract: A facile peptide nucleic acid microarray-based fluorometric method was developed for sensitive and specific detection of EGFR mutation by using rolling circle amplification, graphene oxide, and a fluorescently-labeled detection probe. read more here.
Keywords: egfr mutation; microarray based; rolling circle; sensitive specific ... See more keywords
GATA1 Is a Sensitive and Specific Nuclear Marker for Erythroid and Megakaryocytic Lineages
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqx018
Abstract: Objectives GATA binding factor 1 (GATA1) is a transcription factor essential for erythromegakaryocytic differentiation. Given its function in lineage specification, we sought to evaluate the immunohistochemical profile of GATA1 in normal marrow and acute leukemia… read more here.
Keywords: gata1; megakaryocytic lineages; erythroid megakaryocytic; marker ... See more keywords
A Sensitive and Specific ESI-Positive LC–MS/MS Method for the Quantitation of Estrogens in Human Serum in Under Three Minutes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Chromatographic Science"
DOI: 10.1093/chromsci/bmaa104
Abstract: Abstract Amplifex Diene reagent was employed to derivatize estradiol (E2) to enhance the analyte signal at low picogram concentrations. This derivatization enabled measurement of E2 (and other estrogens) in ESI+ mode, earlier retention times for… read more here.
Keywords: positive method; specific esi; method; esi positive ... See more keywords
BIOM-54. A RAPID GENOTYPING PANEL FOR SENSITIVE AND SPECIFIC SEGREGATION OF CNS PATHOLOGIES
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.051
Abstract: Primary central nervous system lymphoma (PCNSL) remains challenging to diagnose due to nonspecific clinical and radiologic features and low diagnostic yields of cerebrospinal fluid (CSF) studies. We sought to characterize the diagnostic approach of suspected… read more here.
Keywords: glioma; biom rapid; csf; pcnsl ... See more keywords
TRPS1 expression is sensitive and specific for primary extramammary Paget disease.
Sign Up to like & getrecommendations! Published in 2023 at "Histopathology"
DOI: 10.1111/his.14908
Abstract: AIMS Extramammary Paget disease (EMPD) is an epithelial neoplasm that can occur at many sites, including the vulva and scrotum. EMPD is characterised by the presence of neoplastic cells, in single cells and clusters, that… read more here.
Keywords: extramammary paget; vulva; empd; sensitive specific ... See more keywords
A commentary on “A rapid, sensitive and specific assay to measure TF activity based on chromogenic determination of thrombin generation”
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15635
Abstract: Why – one might ask – should a methods paper deserve a commentary? Usually, it is when a method is technologically or conceptually novel. That is not the case with the article by Østerud et… read more here.
Keywords: protease; measure activity; cofactor; activity ... See more keywords
Sensitive and specific CRISPR diagnostics.
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.356.6336.392-h
Abstract: CRISPR Technology Methods are needed that can easily detect nucleic acids that signal the presence of pathogens, even at very low levels. Gootenberg et al. combined the allele-specific sensing ability of CRISPR-Cas13a with recombinase polymerase… read more here.
Keywords: crispr; science; specific crispr; sensitive specific ... See more keywords