High Diastolic Sodium Influx in Heart Failure has Drug-Sensitivities Like Late Sodium Current, but Produces Inward Current at Diastolic Potentials
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DOI: 10.1016/j.bpj.2016.11.1802
Abstract: Heart failure (HF) affects over 6 million people, enhances arrhythmogenesis and is associated with elevated intracellular [Na] ([Na]i), which impacts Ca handling via Na/Ca exchange. HF myocytes exhibit increased late Na current (INaL), typically insufficient… read more here.
Keywords: inward current; sodium; heart failure; sensitivities like ... See more keywords