Deletion of Type 2 Metabotropic Glutamate Receptor Decreases Sensitivity to Cocaine Reward in Rats.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.06.046
Abstract: Cocaine users show reduced expression of the metabotropic glutamate receptor (mGluR2), but it is not clear whether this is a predisposing trait for addiction or a consequence of drug exposure. In this study, we found… read more here.
Keywords: mglur2; cocaine; cocaine reward; sensitivity cocaine ... See more keywords
Association of dopamine D2-like and D3 receptor function with initial sensitivity to cocaine reinforcement in male rhesus monkeys
Sign Up to like & getrecommendations! Published in 2023 at "Brain Research"
DOI: 10.2139/ssrn.4333048
Abstract: Identifying neurobiological characteristics that predict the development of cocaine use disorder would be of great value in prevention efforts. Because of their importance in mediating the abuse-related effects of cocaine, brain dopamine receptors are logical… read more here.
Keywords: sensitivity cocaine; sensitivity; d2r availability; dopamine ... See more keywords