Associating drug sensitivity with differentiation status identifies effective combinations for acute myeloid leukemia
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DOI: 10.1182/bloodadvances.2021006307
Abstract: Key Points Combined targeting of AML patient cells with p38 MAPK and BCL2 inhibitors overcomes monocytic-associated resistance to VEN. Exploiting complementary drug sensitivity profiles with respect to leukemic differentiation state affords enhanced efficacy in AML. read more here.
Keywords: drug; sensitivity differentiation; associating drug; drug sensitivity ... See more keywords