A high‐sensitivity HPLC‐ELSD method for HPMC‐AS quantification and its application in elucidating the release mechanism of HPMC‐AS based amorphous solid dispersions
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DOI: 10.1016/j.ejps.2018.07.007
Abstract: &NA; Hydroxypropyl methylcellulose acetate succinate (HPMC‐AS) is one of the most widely used polymers used in amorphous solid dispersions (ASD) for solubility and bioavailability enhancement of poorly water‐soluble drugs. Once released from ASDs, HPMC‐AS was… read more here.
Keywords: hpmc based; hpmc; high sensitivity; method ... See more keywords