Combinations of self‐reported rhinitis, conjunctivitis, and asthma predicts IgE sensitization in more than 25,000 Danes
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12013
Abstract: Abstract Background Allergic rhinitis (AR), allergic conjunctivitis (AC), and asthma composing multiple phenotypes and improved understanding of these phenotypes and their respective risk factors are needed. Objectives The objective of this study was to define… read more here.
Keywords: sige sensitization; prevalence; conjunctivitis asthma; self reported ... See more keywords
Fractional exhaled nitric oxide levels in relation to work-related respiratory burden and sensitization to wheat flour and multigrain in bakers.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and translational allergy"
DOI: 10.1002/clt2.12018
Abstract: BACKGROUND Work-related lower airway symptoms (WR-LAS), rhinitis (WRR), and asthma (WRA) are very common among bakers, due to airborne exposure to wheat flour and multigrain. Limited data is available regarding fractional exhaled nitric oxide (FeNO)… read more here.
Keywords: wheat flour; respiratory burden; sensitization; work related ... See more keywords
Environmental and sensitization variations among asthma and/or rhinitis patients between 2008 and 2018 in China
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12116
Abstract: Abstract Background Little is known about the changes in allergen sensitization in China secondary to the environmental variations over the past decade. We aimed at investigating the variations in sensitization among asthma and/or rhinitis patients… read more here.
Keywords: asthma rhinitis; increase; sensitization; china ... See more keywords
Prevalence of sensitization to molecular food allergens in Europe: A systematic review
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12175
Abstract: Abstract Background Recent reports indicate that the prevalence of food allergy is increasing, but accurate estimates remain a challenge due to cross‐reactivity and limited use of precise diagnostic methods. Molecular allergy diagnostics, in which sensitization… read more here.
Keywords: food; prevalence; sensitization; molecular food ... See more keywords
Maternal separation increases later immobility during forced swim in guinea pig pups: evidence for sensitization of a depressive‐like state
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Psychobiology"
DOI: 10.1002/dev.21444
Abstract: Early-life stress is thought to increase later vulnerability for developing depressive illness by sensitizing underlying stress-responsive systems. Guinea pig pups separated from their mother and isolated in a novel cage for 3 hr exhibit a sensitized… read more here.
Keywords: guinea; guinea pig; pig pups; separation ... See more keywords
Sensitization of depressive-like behavior is attenuated by disruption of prostaglandin synthesis days following brief early attachment-figure isolation.
Sign Up to like & getrecommendations! Published in 2022 at "Developmental psychobiology"
DOI: 10.1002/dev.22237
Abstract: Childhood psychological trauma appears to sensitize stress-related neuroinflammatory systems to increase later vulnerability for depression and other stress-related mental disorders. Isolation of guinea pig pups from the maternal attachment figure for 3 h in threatening surroundings… read more here.
Keywords: attachment figure; like behavior; isolation; sensitization ... See more keywords
Stimulating TRPV1 externalization and synthesis in dorsal root ganglion neurons contributes to PGE2 potentiation of TRPV1 activity and nociceptor sensitization
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pain"
DOI: 10.1002/ejp.959
Abstract: Persistent peripheral sensitization contributes to chronic pain. Plasticity of nociceptive dorsal root ganglion (DRG) neurons (nociceptors) induced by pro‐inflammatory mediators contributes to sensitization. Prostaglandin E2 (PGE2) enriched in injured tissues is known not only directly… read more here.
Keywords: root ganglion; dorsal root; trpv1 activity; sensitization ... See more keywords
What determines skin sensitization potency: Myths, maybes and realities. The 500 molecular weight cut‐off: An updated analysis
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DOI: 10.1002/jat.3348
Abstract: It is widely accepted that substances must have a molecular weight (MW) < 500 to penetrate effectively through the skin to induce sensitization. Roberts et al. (2012. Contact Dermatitis 68: 32–41) evaluated a data set… read more here.
Keywords: updated analysis; chemistry; skin sensitization; molecular weight ... See more keywords
Applicability of amino acid derivative reactivity assay (4 mM) for the prediction of skin sensitization by combining multiple alternative methods to evaluate key events
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4283
Abstract: The amino acid derivative reactivity assay (ADRA) is an alternative method for evaluating key event 1 (KE‐1) in the skin sensitization mechanism included in OECD TG442C (OECD, 2021). Recently, we found that ADRA with a… read more here.
Keywords: accuracy; sensitization; prediction; amino acid ... See more keywords
Acceptable surface limits (ASLs) of skin sensitizers derived from the local lymph node assay (LLNA): BrdU‐ELISA EC1.6 values and their relationships to known sensitization potency information
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DOI: 10.1002/jat.4339
Abstract: Skin sensitization is an extremely important risk factor for occupational health and safety, and it would be desirable to set health‐based exposure limits (HBELs) for the quantitative risk assessment (QRA) based on the skin sensitizing… read more here.
Keywords: ec1 values; sensitization; llna brdu; risk ... See more keywords
Assessment of commercial polymers with and without reactive groups using amino acid derivative reactivity assay based on both molar concentration approach and gravimetric approach
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DOI: 10.1002/jat.4395
Abstract: The amino acid derivative reactivity assay (ADRA), an alternative method for testing skin sensitization, has been established based on the molar concentration approach. However, the additional development of gravimetric concentration and fluorescence detection methods has… read more here.
Keywords: sensitization; concentration; amino acid; reactivity assay ... See more keywords