Articles with "sensitized mice" as a keyword



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Remodeling of brain lipidome in methamphetamine-sensitized mice.

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Published in 2017 at "Toxicology letters"

DOI: 10.1016/j.toxlet.2017.07.214

Abstract: Lipids are predominant components of the brain and key regulators for neural structure and function. The effect of methamphetamine (METH) on behavior, cognition as well as memory has been intensively investigated; however, the impact of… read more here.

Keywords: brain lipidome; sensitized mice; remodeling brain; brain ... See more keywords
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Physiological responses to cisplatin using a mouse hypersensitivity model

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Published in 2020 at "Inhalation Toxicology"

DOI: 10.1080/08958378.2020.1737762

Abstract: Abstract Background: The physiological mechanisms underlying the development of respiratory hypersensitivity to cisplatin (CDDP) are not well-understood. It has been suggested that these reactions are likely the result of type I hypersensitivity, but other explanations… read more here.

Keywords: respiratory; sensitized mice; model; cddp ... See more keywords
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Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust

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Published in 2019 at "Respiratory Research"

DOI: 10.1186/s12931-019-1015-0

Abstract: Agriculture exposures are associated with reducing the risk of allergy and asthma in early life; yet, repeated exposures later in life are associated with chronic bronchitis and obstructive pulmonary diseases. The objective of this study… read more here.

Keywords: ova ode; agriculture; ode; organic dust ... See more keywords
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Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice

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Published in 2022 at "Iranian Journal of Basic Medical Sciences"

DOI: 10.22038/ijbms.2022.65622.14433

Abstract: Objective(s): Although various studies have revealed the beneficial effects of crocin (derived from saffron), such as anti-inflammatory, anti-cancer, antioxidant, and immune modulator, however, its exact mechanism is unknown. The present study aimed to investigate the… read more here.

Keywords: lung tissue; mir 106a; expression; mir 146a ... See more keywords
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IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice

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Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.596772

Abstract: Food allergies are common, costly and potentially life-threatening disorders. They are driven by Th2, but inhibited by Th1 reactions. There is also evidence indicating that IL-2 agonist treatment inhibits allergic sensitization through expansion of regulatory… read more here.

Keywords: food allergy; sensitized mice; agonist treatment; allergen ... See more keywords
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Type IV collagen reduces MUC5AC secretion in the lungs of ovalbumin-sensitized mice

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.851374

Abstract: Mucin 5AC (MUC5AC) is excessively secreted in the respiratory tract of patients with asthma. Suppressing this secretion is important for improving the air passages, which facilitates easy breathing. We have previously reported that the addition… read more here.

Keywords: type collagen; muc5ac secretion; collagen; sensitized mice ... See more keywords
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Lack of Ecto-5′-Nucleotidase Protects Sensitized Mice against Allergen Challenge

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12050697

Abstract: Ecto-5′-nucleotidase (CD73), the ectoenzyme that together with CD39 is responsible for extracellular ATP hydrolysis and adenosine accumulation, regulates immune/inflammatory processes by controlling innate and acquired immunity cell functions. We previously demonstrated that CD73 is required… read more here.

Keywords: allergen challenge; lack ecto; ecto nucleotidase; sensitized mice ... See more keywords