The making of a nucleic acid sensor at the dawn of jawed vertebrate evolution
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DOI: 10.1126/sciadv.ado7464
Abstract: Self and nonself discrimination is fundamental to immunity. However, it remains largely enigmatic how the mechanisms of distinguishing nonself from self originated. As an intracellular nucleic acid sensor, protein kinase R (PKR) recognizes double-stranded RNA… read more here.
Keywords: nucleic acid; sensor; making nucleic; sensor dawn ... See more keywords