Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1
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DOI: 10.1038/s41598-017-00455-7
Abstract: Screening of a carefully selected library of 5,195 small molecules identified 34 hit compounds that interact with the regulatory cyclic nucleotide-binding domain (CNB) of the cAMP sensor, EPAC1. Two of these hits (I942 and I178)… read more here.
Keywords: agonist; small molecule; partial agonist; sensor epac1 ... See more keywords