The C2A domain of synaptotagmin is an essential component of the calcium sensor for synaptic transmission
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DOI: 10.1371/journal.pone.0228348
Abstract: The synaptic vesicle protein, synaptotagmin, is the principle Ca2+ sensor for synaptic transmission. Ca2+ influx into active nerve terminals is translated into neurotransmitter release by Ca2+ binding to synaptotagmin’s tandem C2 domains, triggering the fast,… read more here.
Keywords: synaptic transmission; c2a domain; hydrophobic residues; c2a ... See more keywords