Global protein dynamics as communication sensors in peptide synthetase domains
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DOI: 10.1126/sciadv.abn6549
Abstract: Biological activity is governed by the timely redistribution of molecular interactions, and static structural snapshots often appear insufficient to provide the molecular determinants that choreograph communication. This conundrum applies to multidomain enzymatic systems called nonribosomal… read more here.
Keywords: global protein; communication; sensors peptide; protein dynamics ... See more keywords