SEP‐363856 exerts neuroprotection through the PI3K/AKT/GSK‐3β signaling pathway in a dual‐hit neurodevelopmental model of schizophrenia‐like mice
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DOI: 10.1002/ddr.22225
Abstract: Schizophrenia (SZ) is a serious, destructive neurodevelopmental disorder. Antipsychotic medications are the primary therapy approach for this illness, but it's important to pay attention to the adverse effects as well. Clinical studies for SZ are… read more here.
Keywords: akt gsk; sep 856; model; pi3k akt ... See more keywords
The Potential Antidepressant Action of Duloxetine Co-Administered with the TAAR1 Receptor Agonist SEP-363856 in Mice
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DOI: 10.3390/molecules27092755
Abstract: Here, we explored the possible interaction between duloxetine and SEP-363856 (SEP-856) in depression-related reactions. The results showed that oral administration of duloxetine showed powerful antidepressant-like effects in both the forced swimming test (FST) and the… read more here.
Keywords: antidepressant like; sep 363856; duloxetine; duloxetine sep ... See more keywords