Separation orthogonality in liquid chromatography-mass spectrometry for proteomic applications: comparison of 16 different two-dimensional combinations.
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DOI: 10.1021/acs.analchem.9b05407
Abstract: Peptide separation orthogonality for 16 different 2D LC-ESI MS systems has been evaluated. To compare and contrast the behavior of the first dimension columns, a large proteomic retention dataset of ~30,000 tryptic peptides was collected… read more here.
Keywords: separation; first dimension; liquid chromatography; separation orthogonality ... See more keywords