Enantiomeric separation and quantification of R/S-amphetamine in serum using semi-automated liquid-liquid extraction and ultra-high performance supercritical fluid chromatography-tandem mass spectrometry.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2879
Abstract: The amphetamine molecule contains a chiral center and its enantiomers exhibit differences in pharmacological effects, with the S-enantiomer mediating most of the central nervous system stimulating activity. The majority of prescribed amphetamine consists of the… read more here.
Keywords: quantification amphetamine; enantiomeric separation; amphetamine; separation quantification ... See more keywords
Separation and quantification of Imidazoles in atmospheric particles using LC-Orbitrap-MS.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of separation science"
DOI: 10.1002/jssc.201900689
Abstract: A method using ultra high performance liquid chromatography coupled to a high resolution Orbitrap mass spectrometer was developed to identify and quantify imidazoles in aqueous extracts of aerosol particles. The aqueous particle extract was used… read more here.
Keywords: sample; imidazoles atmospheric; separation quantification; atmospheric particles ... See more keywords
A novel and simple dynamic coating capillary electrophoresis method for the chiral separation and quantification of mitiglinide enantiomers using hydroxyethyl cellulose as a dynamic coating agent.
Sign Up to like & getrecommendations! Published in 2022 at "Die Pharmazie"
DOI: 10.1691/ph.2022.1166
Abstract: A capillary electrophoretic method for the chiral separation and quantification of mitiglinide (MTG) enantiomers is described (less than 9.5 min) with resolution value Rs = 5.25 and with excellent peak shapes after performing the dynamically… read more here.
Keywords: dynamic coating; method; separation; coating agent ... See more keywords