USF2 exacerbates sepsis-induced acute kidney injury and ferroptosis through LPCAT3-mediated NRF2/HO-1/GPX4 pathway.
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DOI: 10.1097/shk.0000000000002588
Abstract: ABSTRACT Background: Sepsis-acute kidney injury (AKI) is a common complication in critically ill patients with a very high mortality rate. Lysophosphatidylcholine acyltransferase 3 (LPCAT3) is crucial in lipid metabolism; however, its role in the pathogenesis… read more here.
Keywords: sepsis aki; lpcat3; nrf2 gpx4; hk2 cells ... See more keywords