Articles with "sepsis model" as a keyword



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Examination of antimicrobial effect of fluoxetine in experimental sepsis model: An in vivo study

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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23240

Abstract: Since most infectious diseases can develop into sepsis, it is still a major medical problem. Some in‐vivo studies showed promising properties of fluoxetine in the treatment of infections. This study aims the antimicrobial effect of… read more here.

Keywords: sepsis; effect; fluoxetine; experimental sepsis ... See more keywords
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Protective Therapy with Mitochondria Isolated from Mesenchymal Stromal Cells in a Sepsis Model

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Published in 2020 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2020.03.126

Abstract: Background & Aim In vivo mitochondrial transfer of mesenchymal stromal cells (MSCs) to immune cells, alveolar and bronchial epithelial cells resulted in metabolic and functional improvements. Thus, we hypothesized that naked mitochondria isolated from MSCs… read more here.

Keywords: sepsis; epithelial cells; mito treatment; sepsis model ... See more keywords
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Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study.

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Published in 2017 at "Acta cirurgica brasileira"

DOI: 10.1590/s0102-865020170030000001

Abstract: Purpose: To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model. Methods: Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal… read more here.

Keywords: correlation; sepsis model; abdominal sepsis; micro pet ... See more keywords
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Effects of epinephrine on heart rate variability and cytokines in a rat sepsis model

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Published in 2018 at "Bosnian Journal of Basic Medical Sciences"

DOI: 10.17305/bjbms.2018.3565

Abstract: Catecholamines have both anti-inflammatory and vasoactive properties. A decreased cardiac response to catecholamines has been associated with a high risk of death in sepsis and septic shock. The aim of this study was to investigate… read more here.

Keywords: sepsis; sepsis model; group; heart rate ... See more keywords
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The effects of hydroxyurea on proinflammatory cytokine and tissue histopathology in an experimental sepsis model.

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Published in 2022 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202201_27880

Abstract: OBJECTIVE The diagnosis and treatment of sepsis are costly to healthcare services, and it is an important disease with high mortality rates. In the pathogenesis of sepsis, for which we still cannot provide a complete… read more here.

Keywords: sepsis; cytokine; histopathology; sepsis model ... See more keywords
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Astragalus polysaccharide protects sepsis model rats after cecum ligation and puncture

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Published in 2022 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2022.1020300

Abstract: To investigate the protective effect and mechanism of Astragalus polysaccharide (APS) on septic rats, the present project applied APS at concentrations of 400, 600, and 800 mg/kg/d to rats for prophylactic administration for 7 d,… read more here.

Keywords: cecum ligation; astragalus polysaccharide; ligation puncture; group ... See more keywords

Pneumococcal BgaA Promotes Host Organ Bleeding and Coagulation in a Mouse Sepsis Model

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Published in 2022 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2022.844000

Abstract: Streptococcus pneumoniae is a major cause of invasive diseases such as pneumonia, meningitis, and sepsis, with high associated mortality. Our previous molecular evolutionary analysis revealed that the S. pneumoniae gene bgaA, encoding the enzyme β-galactosidase… read more here.

Keywords: sepsis; coagulation; bgaa; mouse sepsis ... See more keywords
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The Study on the Regulation of Th Cells by Mesenchymal Stem Cells Through the JAK-STAT Signaling Pathway to Protect Naturally Aged Sepsis Model Rats

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.820685

Abstract: Sepsis is the leading cause of death among patients, especially elderly patients, in intensive care units worldwide. In this study, we established a sepsis model using naturally aged rats and injected 5×106 umbilical cord-derived MSCs… read more here.

Keywords: sepsis; stat signaling; signaling pathway; jak stat ... See more keywords
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Protocol for a Sepsis Model Utilizing Fecal Suspension in Mice: Fecal Suspension Intraperitoneal Injection Model

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Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.765805

Abstract: Background Various animal models of sepsis have been developed to optimize sepsis treatment. However, therapeutic agents that were successful in animal models were rarely effective in human clinical trials. The cecal ligation and puncture (CLP)… read more here.

Keywords: sepsis; fecal suspension; suspension intraperitoneal; model ... See more keywords
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[Immune intervention of human umbilical cord mesenchymal stem cells on sepsis rats].

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Published in 2017 at "Zhonghua wei zhong bing ji jiu yi xue"

DOI: 10.3760/cma.j.issn.2095-4352.2017.08.007

Abstract: OBJECTIVE To investigate the effect of human umbilical cord mesenchymal stem cells (UC-MSCs) on immune cells and inflammatory factors in septic rats. METHODS 184 male Sprague-Dawley (SD) rats were divided into normal control group (n… read more here.

Keywords: hours operation; sepsis model; operation; group ... See more keywords