Simultaneous Determination of Ten Active Components From Jinhongtang Granule in Rat Plasma by LC-MS/MS and its Application to a Comparative Pharmacokinetic Study in Normal and Sepsis Rats In Vivo and In Vitro.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmac043
Abstract: Jinhongtang granule (JHT) is a traditional Chinese medicine formula used for treatment of infection diseases including severe COVID-19. However, pharmacokinetics of JHT was unknown, especially in infection condition. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method… read more here.
Keywords: sepsis; active components; normal sepsis; ten active ... See more keywords
The effects of chrysin on lipopolysaccharide-induced sepsis in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13359
Abstract: Chrysin (CR) is a flavone found in propolis and many plants. Lipopolysaccharide (LPS) is a component of the cell wall of gram-negative bacteria that causes sepsis. The purpose of this study was to investigate the… read more here.
Keywords: sepsis; induced sepsis; lipopolysaccharide induced; chrysin lipopolysaccharide ... See more keywords
Geraniol Ameliorates Sepsis in Neonatal Rats by Regulating Calprotectin and Inflammatory Response
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Food and Nutrition Research"
DOI: 10.12691/jfnr-9-11-1
Abstract: Sepsis is characterized by systemic infection that causes multiple organ dysfunction and is associated with a high mortality rate in the paediatric intensive care unit. In the present study, we investigated the effect of geraniol… read more here.
Keywords: sepsis neonatal; sepsis; neonatal rats; sepsis rats ... See more keywords
Effect of Celecoxib and Infliximab against Multiple Organ Damage Induced by Sepsis in Rats: A Comparative Study
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DOI: 10.3390/biomedicines10071613
Abstract: In cases of sepsis, the immune system responds with an uncontrolled release of proinflammatory cytokines and reactive oxygen species. The lungs, kidneys, and liver are among the early impacted organs during sepsis and are a… read more here.
Keywords: sepsis; celecoxib; clx ifx; study ... See more keywords