Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities
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DOI: 10.1016/j.ebiom.2020.103044
Abstract: Sepsis is a major health problem worldwide. As the number of sepsis cases increases, so does the number of sepsis survivors who suffer from “post-sepsis syndrome” after hospital discharge. This syndrome involves deficits in multiple… read more here.
Keywords: sepsis; therapeutic opportunities; pathophysiology; post sepsis ... See more keywords
GENETIC DELETION OF TRANSLOCATOR PROTEIN EXACERBATES POST-SEPSIS SYNDROME WITH ACTIVATION OF THE C1Q PATHWAY IN SEPTIC MOUSE MODEL
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DOI: 10.1097/shk.0000000000002030
Abstract: ABSTRACT Significant numbers of patients who survive sepsis exhibit psychiatric and cognitive impairments, termed post-sepsis syndrome. Understanding the underlying pathophysiology is essential to develop effective therapies. Translocator protein 18 kDa (TSPO) is a multifaceted mitochondrial… read more here.
Keywords: sepsis; c1q pathway; sepsis syndrome; post sepsis ... See more keywords