Location is the key to function: HMGB1 in sepsis and trauma‐induced inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3mir1218-497r
Abstract: High mobility group box 1 (HMGB1) is a multifunctional nuclear protein, probably known best as a prototypical alarmin or damage‐associated molecular pattern (DAMP) molecule when released from cells. However, HMGB1 has multiple functions that depend… read more here.
Keywords: hmgb1 sepsis; sepsis trauma; function; location ... See more keywords
EMERGING ROLE OF EXTRACELLULAR RNA IN INNATE IMMUNITY, SEPSIS, AND TRAUMA
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DOI: 10.1097/shk.0000000000002032
Abstract: ABSTRACT Sepsis and trauma remain the leading causes of morbidity and mortality. Our understanding of the molecular pathogenesis in the development of multiple organ dysfunction in sepsis and trauma has evolved as more focus is… read more here.
Keywords: sepsis; innate immunity; sepsis trauma; role ... See more keywords
Impact of Sex Differences on Mortality in Patients With Sepsis After Trauma: A Nationwide Cohort Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.678156
Abstract: Objective Sepsis is the leading cause of death in intensive care units, and sepsis after trauma is associated with increased mortality rates. However, the characteristics of sepsis after trauma remain unknown, and the influence of… read more here.
Keywords: hospital mortality; group; study; mortality ... See more keywords