Regulation of septin phosphorylation: SEPT12 phosphorylation in sperm septin assembly
Sign Up to like & getrecommendations! Published in 2019 at "Cytoskeleton"
DOI: 10.1002/cm.21491
Abstract: The sperm annulus, a septin‐based ring structure, is important for reproductive physiology. It is composed of SEPT12‐based septin core complex followed by assembling as octameric filament. In clinical examinations, mutations of Septin12 result in male… read more here.
Keywords: septin; physiology; phosphorylation sept12; phosphorylation ... See more keywords
2019 Cytoskeleton Paper of the Year: A revised order of subunits in mammalian septin complexes
Sign Up to like & getrecommendations! Published in 2020 at "Cytoskeleton"
DOI: 10.1002/cm.21594
Abstract: Cytoskeleton is pleased to announce the 2019 paper of the year. The paper is “A revised order of subunits in mammalian septin complexes” by Deborah C. Mendonca, Joci N. Macedo, Samuel L. Guimaraes, Fernando L.… read more here.
Keywords: cytoskeleton; septin; paper; year ... See more keywords
Simultaneous co-overexpression of Saccharomyces cerevisiae septins Cdc3 and Cdc10 drives pervasive, phospholipid-, and tag-dependent plasma membrane localization.
Sign Up to like & getrecommendations! Published in 2023 at "Cytoskeleton"
DOI: 10.1002/cm.21762
Abstract: Septin proteins contribute to many eukaryotic processes involving cellular membranes. In the budding yeast Saccharomyces cerevisiae, septin hetero-oligomers interact with the plasma membrane (PM) almost exclusively at the future site of cytokinesis. While multiple mechanisms… read more here.
Keywords: localization; septins cdc3; septin; cdc3 cdc10 ... See more keywords
Septin 4 controls CCNB1 stabilization via APC/CCDC20 during meiotic G2/M transition in mouse oocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30498
Abstract: In mammals, oocytes are arrested at G2/prophase for a long time, which is called germinal vesicle (GV) arrest. After puberty, fully-grown oocytes are stimulated by a gonadotropin surge to resume meiosis as indicated by GV… read more here.
Keywords: apc ccdc20; transition; meiotic transition; via apc ... See more keywords
Septin 9 has Two Polybasic Domains Critical to Septin Filament Assembly and Golgi Integrity
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DOI: 10.1016/j.isci.2020.101042
Abstract: ‘‘Figure 2C depicts representative data from a total of two individual replicates. Quantification of the data is challenging to perform due to the fact that septin 9 in isolation is prone to spontaneous cleavage. Additional… read more here.
Keywords: septin two; septin; two polybasic; critical septin ... See more keywords
Interplay of septin amphipathic helices in sensing membrane-curvature and filament bundling
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e20-05-0303
Abstract: The curvature of the membrane defines cell shape. Septins are GTP-binding proteins that assemble into heteromeric complexes and polymerize into filaments at areas of micron-scale membrane curvature. An amphipathic helix (AH) domain within the septin… read more here.
Keywords: membrane curvature; curvature; septin; domain ... See more keywords
Septin 9 Methylation in Nasopharyngeal Swabs: A Potential Minimally Invasive Biomarker for the Early Detection of Nasopharyngeal Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Disease Markers"
DOI: 10.1155/2020/7253531
Abstract: Nasopharyngeal carcinoma (NPC) is highly prevalent in Southeast Asia, and an unfavorable outcome is usually attributed to advanced stage NPC. Current methods for the early diagnosis of NPC have limitations in clinical practice. The aim… read more here.
Keywords: methylation; npc; septin; detection nasopharyngeal ... See more keywords
Turgor-dependent and coronin-mediated F-actin dynamics drive septin disc-to-ring remodeling in the blast fungus.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.251298
Abstract: The fungus Magnaporthe oryzae uses a specialized pressure-generating infection cell called an appressorium to break into rice leaves and initiate disease. Appressorium functionality is dependent on the formation of a cortical septin ring during its… read more here.
Keywords: coronin; septin disc; septin; disc ring ... See more keywords
Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.258484
Abstract: Septin GTP-binding proteins contribute essential biological functions that range from the establishment of cell polarity to animal tissue morphogenesis. Human septins in cells form hetero-octameric septin complexes containing the ubiquitously expressed SEPT9. Despite the established… read more here.
Keywords: sept9; recombinant human; human septin; septin ... See more keywords
Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.26836
Abstract: ABSTRACT Epithelial Ovarian Cancer (EOC) is associated with dismal survival rates due to the fact that patients are frequently diagnosed at an advanced stage and eventually become resistant to traditional chemotherapeutics. Hence, there is a… read more here.
Keywords: epithelial ovarian; septin; septin overexpressed; proliferation ... See more keywords
Septins From Protists to People
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.824850
Abstract: Septin GTPases form nonpolar heteropolymers that play important roles in cytokinesis and other cellular processes. The ability to form heteropolymers appears to be critical to many septin functions and to have been a major driver… read more here.
Keywords: core septins; septins protists; protists people; biology ... See more keywords