Leveraging genome-wide datasets to quantify the functional role of the anti-Shine–Dalgarno sequence in regulating translation efficiency
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DOI: 10.1098/rsob.160239
Abstract: Studies dating back to the 1970s established that sequence complementarity between the anti-Shine–Dalgarno (aSD) sequence on prokaryotic ribosomes and the 5′ untranslated region of mRNAs helps to facilitate translation initiation. The optimal location of aSD… read more here.
Keywords: translation efficiency; sequence complementarity; asd sequence; translation ... See more keywords
mRNA/protein sequence complementarity and its determinants: The impact of affinity scales
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DOI: 10.1371/journal.pcbi.1005648
Abstract: It has recently been demonstrated that the nucleobase-density profiles of mRNA coding sequences are related in a complementary manner to the nucleobase-affinity profiles of their cognate protein sequences. Based on this, it has been proposed… read more here.
Keywords: mrna protein; protein sequence; sequence complementarity; complementarity ... See more keywords