Coding potential and sequence conservation of SARS-CoV-2 and related animal viruses
Sign Up to like & getrecommendations! Published in 2020 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2020.104353
Abstract: Abstract In December 2019, a novel human-infecting coronavirus (SARS-CoV-2) was recognized in China. In a few months, SARS-CoV-2 has caused thousands of disease cases and deaths in several countries. Phylogenetic analyses indicated that SARS-CoV-2 clusters… read more here.
Keywords: conservation sars; sequence conservation; potential sequence; cov related ... See more keywords
Alignment-free estimation of sequence conservation for identifying functional sites using protein sequence embeddings
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac599
Abstract: Abstract Protein language modeling is a fast-emerging deep learning method in bioinformatics with diverse applications such as structure prediction and protein design. However, application toward estimating sequence conservation for functional site prediction has not been… read more here.
Keywords: functional sites; sequence conservation; alignment free; conservation ... See more keywords