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Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1076
Abstract: Roxadustat inhibits breast cancer resistance protein and organic anion transporting polypeptide 1B1, which can affect coadministered statin concentrations. Three open‐label, 1‐sequence crossover phase 1 studies in healthy subjects were conducted to assess effects from steady‐state…
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Keywords:
roxadustat;
label sequence;
sequence crossover;
atorvastatin ... See more keywords
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Published in 2019 at "American Journal of Cardiovascular Drugs"
DOI: 10.1007/s40256-019-00348-2
Abstract: BackgroundThis was an open-label, phase I, nonrandomized, single-sequence, crossover study to evaluate the effect of concomitant administration of multiple doses of clarithromycin on the single-dose exposure, safety, and tolerability of apixaban in healthy subjects.MethodsIn total,…
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Keywords:
sequence crossover;
administration;
single sequence;
clarithromycin ... See more keywords