AutoESDCas: A Web-Based Tool for the Whole-Workflow Editing Sequence Design for Microbial Genome Editing Based on the CRISPR/Cas System.
Sign Up to like & getrecommendations! Published in 2024 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.4c00063
Abstract: Genome editing is the basis for the modification of engineered microbes. In the process of genome editing, the design of editing sequences, such as primers and sgRNA, is very important for the accurate positioning of… read more here.
Keywords: genome editing; design; sequence design; editing sequence ... See more keywords
Protein sequence design with a learned potential
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28313-9
Abstract: The task of protein sequence design is central to nearly all rational protein engineering problems, and enormous effort has gone into the development of energy functions to guide design. Here, we investigate the capability of… read more here.
Keywords: design; design learned; sequence design; protein ... See more keywords
Pulse sequence design for high field NMR with NV centers in dipolarly coupled samples
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-025-15899-5
Abstract: Diamond-based quantum sensors have enabled high-resolution NMR spectroscopy at the microscale in scenarios where fast molecular motion averages out dipolar interactions among target nuclei. However, in samples with low-diffusion, ubiquitous dipolar couplings challenge the extraction… read more here.
Keywords: coupled samples; dipolarly coupled; sequence design; high field ... See more keywords
Polymer sequence design via molecular simulation-based active learning.
Sign Up to like & getrecommendations! Published in 2023 at "Soft matter"
DOI: 10.1039/d2sm01193j
Abstract: Molecular-scale interactions and chemical structures offer an enormous opportunity to tune material properties. However, designing materials from their molecular scale is a grand challenge owing to the practical limitations in exploring astronomically large design spaces… read more here.
Keywords: active learning; sequence design; design via; design ... See more keywords
R3Design: deep tertiary structure-based RNA sequence design and beyond
Sign Up to like & getrecommendations! Published in 2024 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbae682
Abstract: Abstract The rational design of Ribonucleic acid (RNA) molecules is crucial for advancing therapeutic applications, synthetic biology, and understanding the fundamental principles of life. Traditional RNA design methods have predominantly focused on secondary structure-based sequence… read more here.
Keywords: structure based; structure; biology; sequence design ... See more keywords
Deep learning of protein sequence design of protein–protein interactions
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac733
Abstract: Motivation As more data of experimentally determined protein structures is becoming available, data-driven models to describe protein sequence-structure relationship become more feasible. Within this space, the amino acid sequence design of protein-protein interactions has still… read more here.
Keywords: protein interactions; protein protein; sequence design; protein ... See more keywords
RobuT-Net: Dual-CNN-Based Robust Training Sequence Design for IoT Systems
Sign Up to like & getrecommendations! Published in 2024 at "IEEE Internet of Things Journal"
DOI: 10.1109/jiot.2023.3331111
Abstract: This letter proposes a new methodology for training sequence design in Internet of Things (IoT) systems based on deep learning, called RobuT-Net. The proposed RobuT-Net is constructed via a dual convolutional neural network (CNN) architecture… read more here.
Keywords: robut net; cnn; training sequence; iot systems ... See more keywords
Cooperative Sensing Sequence Design for Distributed OFDM Based Stations Under Time-Frequency Structure Constraints
Sign Up to like & getrecommendations! Published in 2025 at "IEEE Signal Processing Letters"
DOI: 10.1109/lsp.2025.3577125
Abstract: The orthogonal frequency division multiplexing (OFDM) sequences are widely used in 4 G, 5 G and integrated sensing and communication (ISAC). In this paper, we address the challenge of designing orthogonal OFDM sequences. The weighted… read more here.
Keywords: cooperative sensing; time; sequence design; sequence ... See more keywords
Improved Bare Bones Particle Swarm Optimization for DNA Sequence Design.
Sign Up to like & getrecommendations! Published in 2022 at "IEEE transactions on nanobioscience"
DOI: 10.1109/tnb.2022.3220795
Abstract: DNA computing has efficient computational power, but requires high requirements on the DNA sequences used for coding, and reliable DNA sequences can effectively improve the quality of DNA encoding. And designing reliable DNA sequences is… read more here.
Keywords: dna; dna sequences; sequence design; dna sequence ... See more keywords
A Unified Framework for Low Autocorrelation Sequence Design via Majorization–Minimization
Sign Up to like & getrecommendations! Published in 2017 at "IEEE Transactions on Signal Processing"
DOI: 10.1109/tsp.2016.2620113
Abstract: In this paper, we consider the low autocorrelation sequence design problem. We optimize a unified metric over a general constraint set. The unified metric includes the integrated sidelobe level (ISL) and the peak sidelobe level… read more here.
Keywords: autocorrelation sequence; low autocorrelation; minimization; autocorrelation ... See more keywords
Training Beam Sequence Design for mmWave Tracking Systems With and Without Environmental Knowledge
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Wireless Communications"
DOI: 10.1109/twc.2022.3187167
Abstract: In this paper, we consider a millimeter wave multiple-input single-output tracking system, where the time-varying angle of departure (AoD) is assumed to change following a discrete state Markov process. Depending on whether the associated AoD… read more here.
Keywords: function; beam; sequence design; training beam ... See more keywords