Articles with "sequence signatures" as a keyword



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Evolutionary origin and sequence signatures of the heterodimeric ABCG5/ABCG8 transporter

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Published in 2022 at "Protein Science"

DOI: 10.1002/pro.4297

Abstract: ATP‐binding cassette (ABC) systems, characterized by ABC‐type nucleotide‐binding domains (NBDs), play crucial roles in various aspects of human physiology. Human ABCG5 and ABCG8 form a heterodimeric transporter that functions in the efflux of sterols. We… read more here.

Keywords: evolutionary origin; abcg5 abcg8; transporter; abcg8 ... See more keywords