Use of negative controls in a prescription sequence symmetry analysis to reduce time‐varying bias
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5293
Abstract: There is an increased use in the (prescription) sequence symmetry analysis (PSSA); however, limited studies have incorporated a negative control, and no study has formally quantified and controlled for within‐patient time‐varying bias using a negative… read more here.
Keywords: sequence symmetry; time varying; analysis; prescription sequence ... See more keywords
Obtaining Valid Compatibility Intervals for Sequence Symmetry Analyses Utilizing Active Comparators: A Simulation Study
Sign Up to like & getrecommendations! Published in 2025 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.70160
Abstract: To compare different methods of estimating 95% compatibility intervals (CIs) for the sequence ratio (SR) when performing a sequence symmetry analysis using an active comparator to reduce the risk of time‐varying confounding. read more here.
Keywords: compatibility intervals; obtaining valid; sequence symmetry; valid compatibility ... See more keywords
Sequence symmetry analysis in pharmacovigilance and pharmacoepidemiologic studies
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Epidemiology"
DOI: 10.1007/s10654-017-0281-8
Abstract: Sequence symmetry analysis (SSA) is a method for detecting adverse drug events by utilizing computerized claims data. The method has been increasingly used to investigate safety concerns of medications and as a pharmacovigilance tool to… read more here.
Keywords: sequence symmetry; ssa; symmetry analysis; drug ... See more keywords
Detection of iodixanol-induced allergic reaction signals in Chinese inpatients: a multi-center retrospective database study using prescription sequence symmetry analysis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2024.1298021
Abstract: Objective: This study aimed to explore the signal detection method for allergic reactions induced by inpatient iodixanol injection. Methods: A database of 3,719,217 hospitalized patients from 20 large Chinese general hospitals was processed and analyzed… read more here.
Keywords: using prescription; prescription sequence; sequence symmetry; analysis ... See more keywords