Global analysis of inverted repeat sequences in human gene promoters reveals their non-random distribution and association with specific biological pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.03.014
Abstract: Inverted repeats (IR) play important roles in specific DNA-dependent processes in simple prokaryotes to complex eukaryotes. They are recognized by a variety of proteins including restriction enzymes, helicases and transcription factors. We evaluate the presence… read more here.
Keywords: repeat sequences; biological pathways; global analysis; inverted repeat ... See more keywords
Prevalent Sequences in the Human Genome Can Form Mini i-Motif Structures at Physiological pH.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b07383
Abstract: We report here the solution structure of several repetitive DNA sequences containing d(TCGTTCCGT) and related repeats. At physiological pH, these sequences fold into i-motif like quadruplexes in which every two repeats a globular structure is… read more here.
Keywords: human genome; prevalent sequences; base pairs; form mini ... See more keywords
Abundant CpG-sequences in human genomes inhibit KIR3DL2-expressing NK cells
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.12258
Abstract: Killer Immunoglobulin-like Receptors (KIR) comprise a diverse, highly polymorphic family of cell-surface glycoproteins that are principally expressed by Natural Killer (NK) cells. These innate immune lymphocytes fulfill vital functions in human reproduction and immune responses… read more here.
Keywords: dna sequences; dna; kir3dl2; cpg dna ... See more keywords