Whole‐exome sequencing analysis in 10 families of sporadic microtia with thoracic deformities
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1657
Abstract: Microtia is a congenital malformation of the external ear and may occur as an isolated deformity or as part of a syndrome. Our previous study found a high correlation between microtia and thoracic deformities, thus,… read more here.
Keywords: exome sequencing; thoracic deformities; microtia thoracic; sequencing analysis ... See more keywords
Bioinformatics Pipeline for Transcriptome Sequencing Analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-4035-6_14
Abstract: The development of High Throughput Sequencing (HTS) for RNA profiling (RNA-seq) has shed light on the diversity of transcriptomes. While RNA-seq is becoming a de facto standard for monitoring the population of expressed transcripts in… read more here.
Keywords: transcriptome sequencing; transcriptome; biology; pipeline transcriptome ... See more keywords
An Informative Approach to Single-Cell Sequencing Analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-6037-4_6
Abstract: Recent advances in sequencing technologies enable us to obtain genome, epigenome and transcriptome data in individual cells. In this review, we describe various platforms for single-cell sequencing analysis across multiple layers. We mainly introduce an… read more here.
Keywords: single cell; cell rna; rna seq; cell sequencing ... See more keywords
Exome Sequencing Analysis of Familial Cases of Multiple Sclerosis and a Monozygotic Discordant Twin
Sign Up to like & getrecommendations! Published in 2021 at "Arabian Journal for Science and Engineering"
DOI: 10.1007/s13369-020-05242-7
Abstract: Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease, which leads to neurodegenerative processes that cause neuron demyelination. MS is multifactorial with uncertain etiology, where interactions between genetic makeup of an individual and environmental factors… read more here.
Keywords: etiology; sequencing analysis; multiple sclerosis; exome sequencing ... See more keywords
Development of an Endonuclease V-Assisted Analytical Method for Sequencing Analysis of Deoxyinosine in DNA.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02126
Abstract: Deoxyinosine (dI) is a highly mutagenic lesion that preferentially pairs with deoxycytidine during replication, which may induce A to G transition and ultimately contribute to carcinogenesis. Therefore, finding the site of dI modification in DNA… read more here.
Keywords: modification; dna; sequencing analysis; endonuclease ... See more keywords
Transposon sequencing analysis of Bradyrhizobium diazoefficiens 110spc4
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-92534-z
Abstract: Bradyrhizobium diazoefficiens USDA110 is one of the most effective nitrogen-fixing symbionts of soybeans. Here we carried out a large-scale transposon insertion sequencing (Tn-seq) analysis of strain Bd110spc4, which is derived from USDA110, with the goal… read more here.
Keywords: transposon sequencing; transposon; sequencing analysis; bradyrhizobium diazoefficiens ... See more keywords
Genopo: a nanopore sequencing analysis toolkit for portable Android devices
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-01270-z
Abstract: The advent of portable nanopore sequencing devices has enabled DNA and RNA sequencing to be performed in the field or the clinic. However, advances in in situ genomics require parallel development of portable, offline solutions… read more here.
Keywords: analysis; genopo nanopore; toolkit; nanopore sequencing ... See more keywords
Genome sequencing and analysis of genomic diversity in the locally transmitted SARS‐CoV‐2 in Pakistan
Sign Up to like & getrecommendations! Published in 2022 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.14586
Abstract: Abstract Surveillance of genetic diversity of the SARS‐CoV‐2 is extremely important to detect the emergence of more infectious and deadly strains of the virus. In this study, we evaluated mutational events in the SARS‐CoV‐2 genomes… read more here.
Keywords: genome sequencing; diversity; sequencing analysis; sars cov ... See more keywords
Diazotroph Community Characterization via a High-Throughput nifH Amplicon Sequencing and Analysis Pipeline
Sign Up to like & getrecommendations! Published in 2017 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01512-17
Abstract: ABSTRACT The dinitrogenase reductase gene (nifH) is the most widely established molecular marker for the study of nitrogen-fixing prokaryotes in nature. A large number of PCR primer sets have been developed for nifH amplification, and… read more here.
Keywords: pipeline; diazotroph; analysis; amplicon sequencing ... See more keywords
Transcriptome Sequencing and Analysis of Chilling Tolerance Mutant Tomato under Low Temperature
Sign Up to like & getrecommendations! Published in 2019 at "Russian Journal of Plant Physiology"
DOI: 10.1134/s1021443719010059
Abstract: AbstractΤhe tomato plant (Lycopersicon esculentum Mill.) is particularly vulnerable to chilling injury. Hence research on screening out the cold-resistance gene in tomato is essential to improve tomato yield and quality. We investigated the gene expression… read more here.
Keywords: sequencing analysis; analysis chilling; tomato; transcriptome sequencing ... See more keywords
Recent Advances in High Throughput Sequencing Analysis
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Genomics"
DOI: 10.1155/2017/2454780
Abstract: High-throughput genomic technology has enabled us to screen the entire genome and generate hypotheses at relatively low costs. One of the driving forces in highthroughput genomic technology is high-throughput sequencing (HTS).With its rapid development and… read more here.
Keywords: analysis; advances high; recent advances; sequencing analysis ... See more keywords