PUB053 Panel Based Hybrid Capture Sequencing Assay to Correlate Mutational Load with Response to Immunotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2016.11.2023
Abstract: www.newoncology.de Background: The use of immune checkpoint inhibitors has shown promise in lung cancer as well as several other tumor types. However, two of their limitations are the overall relatively low response rate as well… read more here.
Keywords: mutational load; immunotherapy; response; hybrid capture ... See more keywords
A de novo genome assembly of the dwarfing pear rootstock Zhongai 1
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Data"
DOI: 10.1038/s41597-019-0291-3
Abstract: ‘Zhongai 1’ [(Pyrus ussuriensis × communis) × spp.] is an excellent pear dwarfing rootstock common in China. It is dwarf itself and has high dwarfing efficiency on most of main Pyrus cultivated species when used as inter-stock. Here we… read more here.
Keywords: genome assembly; pyrus; sequencing assay; genome ... See more keywords
Abstract LB081: Concurrent characterization of somatic nucleotide mutations, 5mC, and 5hmC methylation in clinical research samples using a single nanopore sequencing assay
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb081
Abstract: Genomic and epigenomic variants accumulate during cancer progression, resulting in a tumor consisting of heterogeneous collections of cells, or clones, with distinct profiles of genomic and/or epigenomic alterations. The ability to characterize a broad set… read more here.
Keywords: research; using single; sequencing assay; nanopore sequencing ... See more keywords
Clinical validation of the tempus xT next-generation targeted oncology sequencing assay
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.26797
Abstract: We developed and clinically validated a hybrid capture next generation sequencing assay to detect somatic alterations and microsatellite instability in solid tumors and hematologic malignancies. This targeted oncology assay utilizes tumor-normal matched samples for highly… read more here.
Keywords: sequencing assay; clinical validation; targeted oncology; next generation ... See more keywords
A Targeted Sequencing Assay for Serotyping Escherichia coli Using AgriSeq Technology
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.627997
Abstract: The gold standard method for serotyping Escherichia coli has relied on antisera-based typing of the O- and H-antigens, which is labor intensive and often unreliable. In the post-genomic era, sequence-based assays are potentially faster to… read more here.
Keywords: escherichia coli; serotyping escherichia; sequence based; sequencing assay ... See more keywords
A Rapid, Whole Genome Sequencing Assay for Detection and Characterization of Novel Coronavirus (SARS-CoV-2) Clinical Specimens Using Nanopore Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.910955
Abstract: A new human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged at the end of 2019 in Wuhan, China that caused a range of disease severities; including fever, shortness of breath, and coughing. This… read more here.
Keywords: coronavirus sars; coronavirus; sequencing assay; clinical specimens ... See more keywords