Nanopore sequencing and assembly of a human genome with ultra-long reads
Sign Up to like & getrecommendations! Published in 2018 at "Nature Biotechnology"
DOI: 10.1038/nbt.4060
Abstract: We report the sequencing and assembly of a reference genome for the human GM12878 Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore sequencer. 91.2 Gb of sequence data, representing ∼30× theoretical coverage, were… read more here.
Keywords: ultra long; human genome; nanopore sequencing; long reads ... See more keywords
Comparative Genomics of Cyanobacterial Symbionts Reveals Distinct, Specialized Metabolism in Tropical Dysideidae Sponges
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DOI: 10.1128/mbio.00821-19
Abstract: Natural products provide the inspiration for most clinical drugs. With the rise in antibiotic resistance, it is imperative to discover new sources of chemical diversity. Bacteria living in symbiosis with marine invertebrates have emerged as… read more here.
Keywords: hybrid sequencing; metabolism; assembly approach; chemistry ... See more keywords
Comparison of Long-Read Methods for Sequencing and Assembly of Lepidopteran Pest Genomes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010649
Abstract: Lepidopteran species are mostly pests, causing serious annual economic losses. High-quality genome sequencing and assembly uncover the genetic foundation of pest occurrence and provide guidance for pest control measures. Long-read sequencing technology and assembly algorithm… read more here.
Keywords: quality; sequencing assembly; quality genome; high quality ... See more keywords