Emerging pathogens in the fish farming industry and sequencing-based pathogen discovery.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2017.01.025
Abstract: The use of large scale DNA/RNA sequencing has become an integral part of biomedical research. Reduced sequencing costs and the availability of efficient computational resources has led to a revolution in how problems concerning genomics… read more here.
Keywords: based pathogen; sequencing based; emerging pathogens; pathogen discovery ... See more keywords
Review of automated DNA extraction systems for sequencing-based solutions for drug-resistant tuberculosis detection.
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2020.115096
Abstract: Robust clinical specimen nucleic acid extraction instrumentation and methods are critical to the performance of downstream molecular diagnostics for the diagnosis of drug-resistant tuberculosis (DR-TB). Currently, there is a high level of interest in sequencing-based… read more here.
Keywords: extraction; based solutions; drug resistant; sequencing based ... See more keywords
Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types.
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2018.04.017
Abstract: With the advent of new molecular tools, the discovery of new papillomaviruses (PVs) has accelerated during the past decade, enabling the expansion of knowledge about the viral populations that inhabit the human body. Human PVs… read more here.
Keywords: generation novel; generation; next generation; sequencing based ... See more keywords
Next-Generation Sequencing-Based Analysis of the Effects of N1- and N6-Methyldeoxyadenosine Adducts on DNA Transcription.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01764
Abstract: DNA methylation can occur naturally or be induced by various environmental and chemotherapeutic agents. The regioisomeric N1- and N6-methyldeoxyadenosine (1mdA and 6mdA, respectively) represent an important class of methylated DNA adducts. In this study, we… read more here.
Keywords: dna; transcription; dna transcription; next generation ... See more keywords
VSS: Variance-stabilized signals for sequencing-based genomic signals.
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab457
Abstract: MOTIVATION A sequencing-based genomic assay such as ChIP-seq outputs a real-valued signal for each position in the genome that measures the strength of activity at that position. Most genomic signals lack the property of variance… read more here.
Keywords: stabilized signals; variance stabilized; genomic signals; variance ... See more keywords
Exodus: sequencing-based pipeline for quantification of pooled variants
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac319
Abstract: Abstract Summary Next-Generation Sequencing is widely used as a tool for identifying and quantifying microorganisms pooled together in either natural or designed samples. However, a prominent obstacle is achieving correct quantification when the pooled microbes… read more here.
Keywords: quantification; exodus; exodus sequencing; quantification pooled ... See more keywords
Lean Principles to Improve Quality in High-Throughput COVID-19 Testing Using SwabSeq: A Barcoded Sequencing-Based Testing Platform
Sign Up to like & getrecommendations! Published in 2021 at "Laboratory Medicine"
DOI: 10.1093/labmed/lmab069
Abstract: Abstract Objective To describe and quantify the effect of quality control (QC) metrics to increase testing efficiency in a high-complexity, Clinical Laboratory Improvement Amendments–certified laboratory that uses amplicon-based, next generation sequencing for the clinical detection… read more here.
Keywords: quality; six sigma; lean six; sequencing based ... See more keywords
Evaluation of repeat testing of a non‐sequencing based NIPT test on a Finnish general‐risk population
Sign Up to like & getrecommendations! Published in 2021 at "Acta Obstetricia et Gynecologica Scandinavica"
DOI: 10.1111/aogs.14125
Abstract: To evaluate the effect of repeating test failures using an automated, non‐sequencing based non‐invasive prenatal testing test on a general‐risk population in Finland. read more here.
Keywords: general risk; non sequencing; test; sequencing based ... See more keywords
Next‐generation sequencing‐based typing of a new allele HLA‐DQB1*03:01:01:20 in a Chinese family
Sign Up to like & getrecommendations! Published in 2018 at "HLA"
DOI: 10.1111/tan.13216
Abstract: DQB1*03:01:01:20 showed one nucleotide difference when compared to DQB1*03:01:01:01 at 224 (C>T). read more here.
Keywords: based typing; dqb1; sequencing based; next generation ... See more keywords
Characterization of the novel HLA‐B*40:01:51 allele by sequencing‐based typing
Sign Up to like & getrecommendations! Published in 2018 at "HLA"
DOI: 10.1111/tan.13285
Abstract: HLA‐B*40:01:51 differs from HLA‐B*40:01:01 by 2 nucleotide substitutions at position 72 and 126. read more here.
Keywords: characterization novel; allele sequencing; hla; novel hla ... See more keywords
Characterization of the novel HLA‐A*03:315 allele by sequencing‐based typing
Sign Up to like & getrecommendations! Published in 2019 at "HLA"
DOI: 10.1111/tan.13420
Abstract: HLA‐A*03:315 differs from HLA‐A*03:01:01:01 by one nucleotide substitution at codon 285 in exon 5. read more here.
Keywords: characterization novel; allele sequencing; hla 315; novel hla ... See more keywords