ESCMID postgraduate education course: regional capacity building for integration of next-generation sequencing in the clinical microlab.
Sign Up to like & getrecommendations! Published in 2018 at "Microbes and infection"
DOI: 10.1016/j.micinf.2018.02.006
Abstract: Scientifi c picture outside: A minimum spanning tree of a core genome MLST analysis performed during an outbreak. © John Rossen Scientifi c picture inside: A shotgun sequence representing a clinical sample analysed by metagenomics… read more here.
Keywords: capacity; sequencing clinical; course; microbiology ... See more keywords
MINERVA: A Facile Strategy for SARS-CoV-2 Whole-Genome Deep Sequencing of Clinical Samples
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cell"
DOI: 10.1016/j.molcel.2020.11.030
Abstract: Analyzing the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from clinical samples is crucial for the understanding of viral spread and viral evolution, as well as for vaccine development. Existing RNA sequencing methods… read more here.
Keywords: minerva facile; sequencing clinical; sars cov; facile strategy ... See more keywords
The long tail of molecular alterations in non-small cell lung cancer: a single-institution experience of next-generation sequencing in clinical molecular diagnostics
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2018-205032
Abstract: Background Molecular profiling of advanced non-small cell lung cancers (NSCLC) is essential to identify patients who may benefit from targeted treatments. In the last years, the number of potentially actionable molecular alterations has rapidly increased.… read more here.
Keywords: generation sequencing; sequencing clinical; non small; next generation ... See more keywords
Next-generation sequencing in clinical virology: A review of its applications
Sign Up to like & getrecommendations! Published in 2020 at "Pesquisa Agropecuaria Brasileira"
DOI: 10.19045/bspab.2020.90250
Abstract: Next-generation sequencing (NGS) has emerged as the most useful technique for wide-scale detection of infection-causing pathogens. Owing to the increasing demand for cost-effective and quick DNA sequencing protocols, many research groups have reported the use… read more here.
Keywords: virology; sequencing clinical; review; next generation ... See more keywords
Implementation of Exome Sequencing in Clinical Practice for Neurological Disorders
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040813
Abstract: Neurological disorders (ND) are diseases that affect the brain and the central and autonomic nervous systems, such as neurodevelopmental disorders, cerebellar ataxias, Parkinson’s disease, or epilepsies. Nowadays, recommendations of the American College of Medical Genetics… read more here.
Keywords: sequencing clinical; neurological disorders; implementation exome; clinical practice ... See more keywords
High Throughput Sequencing for Clinical Tuberculosis: An Overview
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11111343
Abstract: High throughput sequencing (HTS) can identify the presence of Mycobacterium tuberculosis DNA in a clinical sample while also providing information on drug susceptibility. Multiple studies have provided a context for exploring the clinical application of… read more here.
Keywords: sequencing clinical; high throughput; throughput sequencing; clinical tuberculosis ... See more keywords