TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures
Sign Up to like & getrecommendations! Published in 2019 at "Nature Immunology"
DOI: 10.1038/s41590-019-0544-5
Abstract: High-throughput 3′ single-cell RNA-sequencing (scRNA-seq) allows cost-effective, detailed characterization of individual immune cells from tissues. Current techniques, however, are limited in their ability to elucidate essential immune cell features, including variable sequences of T cell… read more here.
Keywords: seq; scrna seq; sequencing paired; tcr sequencing ... See more keywords
Targeted next-generation DNA sequencing of paired tumor and normal DNA to reveal frequent actionable germline alterations.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.11575
Abstract: 11575Background: Targeted next-generation DNA sequencing of paired tumor and normal DNA samples allows for detection of biologically relevant variants in the tumor with significantly greater accura... read more here.
Keywords: targeted next; sequencing paired; dna sequencing; dna ... See more keywords