CONY: A Bayesian procedure for detecting copy number variations from sequencing read depths
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64353-1
Abstract: Copy number variations (CNVs) are genomic structural mutations consisting of abnormal numbers of fragment copies. Next-generation sequencing of read-depth signals mirrors these variants. Some tools used to predict CNVs by depth have been published, but… read more here.
Keywords: cony; sequencing read; copy number; number variations ... See more keywords
CARE: context-aware sequencing read error correction
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa738
Abstract: MOTIVATION Error correction is a fundamental preprocessing step in many NGS pipelines, in particular for de novo genome assembly. However, existing error correction methods either suffer from high false positive rates since they break reads… read more here.
Keywords: care context; error; sequencing read; error correction ... See more keywords