Is it research or is it clinical? Revisiting an old frontier through the lens of next-generation sequencing technologies.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medical genetics"
DOI: 10.1016/j.ejmg.2018.04.009
Abstract: As next-generation sequencing technologies (NGS) are increasingly used in the clinic, one issue often pointed out in the literature is the fact that their implementation "blurs the line" between research and healthcare. Indeed, NGS data… read more here.
Keywords: research; research clinical; sequencing technologies; next generation ... See more keywords
Deciphering bacterial epigenomes using modern sequencing technologies
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Genetics"
DOI: 10.1038/s41576-018-0081-3
Abstract: Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated residues in bacterial genomes has prevented a full understanding of their functions.… read more here.
Keywords: modern sequencing; using modern; epigenomes using; sequencing technologies ... See more keywords
Next-generation sequencing technologies accelerate advances in T-cell therapy for cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/ely018
Abstract: Next-generation sequencing has produced a large quantity of DNA or RNA sequences related to the processes occurring within tumors and their microenvironment in a reasonable time and cost. These data have been used to guide… read more here.
Keywords: cell therapy; sequencing technologies; cancer; next generation ... See more keywords
Is it the time to integrate novel sequencing technologies into clinical practice?
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000754
Abstract: Purpose of review The aim of this study was to provide insight into how novel next-generation sequencing (NGS) techniques are set to revolutionize clinical practice. Recent findings Advances in sequencing technologies have focused on improved… read more here.
Keywords: novel sequencing; clinical practice; sequencing technologies; disease ... See more keywords
High-throughput DNA sequencing technologies for water and wastewater analysis
Sign Up to like & getrecommendations! Published in 2019 at "Science Progress"
DOI: 10.1177/0036850419881855
Abstract: Conventional microbiological water monitoring uses culture-dependent techniques to screen indicator microbial species such as Escherichia coli and fecal coliforms. With high-throughput, second-generation sequencing technologies becoming less expensive, water quality monitoring programs can now leverage the… read more here.
Keywords: water wastewater; water; sequencing technologies; second generation ... See more keywords
Review of genome sequencing technologies in molecular characterization of influenza A viruses in swine
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/10406387211068023
Abstract: The rapidly evolving antigenic diversity of influenza A virus (IAV) genomes in swine makes it imperative to detect emerging novel strains and track their circulation. We analyzed in our review the sequencing technologies used for… read more here.
Keywords: sequencing technologies; iav; swine iav; influenza ... See more keywords
Editorial: The Transition Era to New Sequencing Technologies and Their Application to Integrative Omics in Molecular Surveillance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.840782
Abstract: The current COVID-19 pandemic highlights the importance of novel molecular technologies and methods for rapid pathogen control (Hufsky et al., 2021). In just a few days, South African researchers recently succeeded in sharing crucial sequence… read more here.
Keywords: new sequencing; molecular surveillance; sequencing technologies; era new ... See more keywords
Application of Single-cell Sequencing Technologies in Reproductive Medicine
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive and Developmental Medicine"
DOI: 10.4103/2096-2924.210691
Abstract: We have recently witnessed the rapid development of various single-cell sequencing technologies. Pioneering single cell assays are now available for the profiling of genome, epigenome, and transcriptome. Single-cell sequencing technologies provide multi-dimensional information on early… read more here.
Keywords: single cell; medicine; sequencing technologies; reproductive medicine ... See more keywords