Spatial sequestration of misfolded proteins in neurodegenerative diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society transactions"
DOI: 10.1042/bst20210862
Abstract: Properly folded, functional proteins are essential for cell health. Cells sustain protein homeostasis, or proteostasis, via protein quality control (PQC) mechanisms. It is currently hypothesized that a breakdown in proteostasis during ageing leads to the… read more here.
Keywords: pqc compartments; sequestration; misfolded proteins; sequestration misfolded ... See more keywords