The ULK complex–LRRK1 axis regulates Parkin-mediated mitophagy via Rab7 Ser-72 phosphorylation
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DOI: 10.1242/jcs.260395
Abstract: ABSTRACT Mitophagy, a type of selective autophagy, specifically targets damaged mitochondria. The ULK complex regulates Parkin-mediated mitophagy, but the mechanism through which the ULK complex initiates mitophagosome formation remains unknown. The Rab7 GTPase (herein referring… read more here.
Keywords: ser phosphorylation; rab7; ulk complex; mitophagy ... See more keywords